DOI > 10.5291/ILL-DATA.7-05-537

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Title

The dynamics of DNA base pair formation on carbon surfaces

Abstract

We propose to measure the dynamics of hydrogen bond formation and proton transfer in adsorbed DNA base pairs, focusing initially on the Guanine-Cytosine (GC) dimer. Therefore, we plan to investigate the dynamics of guanine and cytosine adsorbed on exfoliated graphite with the aim of investigating hydrogen bond formation, tautomerisation rates and proton tunnelling in GC dimers. Measuring the dynamics of bond formation and proton exchange within the GC dimer will allow us to probe with unprecedented detail, the rate of bond formation and proton transfer in a system that is critical for biology and medicine. Furthermore, understanding the interaction of carbon materials with biomolecules is essential for designing novel biomedical and catalytic applications.

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

Marco Sacchi; FOUQUET Peter and TAMTOEGL Anton. (2021). The dynamics of DNA base pair formation on carbon surfaces. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.7-05-537

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