DOI > 10.5291/ILL-DATA.8-02-644

This proposal is publicly available since 07/07/2018

Title

Mechanical properties of myelin multilayers

Abstract

The structure of natural myelin has been extensively studied by diffraction. Nevertheless, none of these studies has been concerned with the mechanical properties of interacting myelin membranes. Here we propose the use of specular and off-specular neutron scattering to study the mechanical properties of membrane multilayers prepared either from whole myelin or from myelin lipids. This will shed light on the role of membrane mechanics in myelin stability, lipid/protein phase separation and demyelination as it occurs in pathological disorders like multiple sclerosis.

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

OLIVEIRA Rafael Gustavo; CAVALCANTI Leide; DEME Bruno; Julio M. Pusterla and SCHNECK Emanuel. (2013). Mechanical properties of myelin multilayers. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-644

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Metadata

Experiment Parameters

  • Environment temperature

    278-320 K
  • Experiment energy

    4.5A
  • Experiment moment

    0.05 < q < 0.5 A-1
  • Experiment res energy

    1%

Sample Parameters

  • Formula

    • Natural myelin and myelin lipids (on SiSiO2)
  • Consistence

    solid/liquid interface
  • Mass

    1
  • Size

    3000
  • Surface

    3000
  • Unit cell A

    100
  • Container

    Humidity chamber for waffers