Mechanical properties of bio-membranes interacting with a model synovial fluid
Ultrathin lipid linings are terminal layers on articular cartilage and are of outmost importance for lubrication in mammalian joints. We will apply specular and offspecular neutron scattering to solid-supported, hyaluronic acid (HA)-interlinked DMPC oligo-bilayers against excess aqueous liquid phases (HA+D2O). The experiments will yield valuable insight into the microscopic mechanical behavior of the lipid coatings and thereby into the underlying mechanism responsible for lubrication. We will extract the compression- and bending moduli of the HA-interlinked lipid membranes by adapted modelling of the shape of the recorded Bragg-sheets in two dimensions (qz and q||). With a preset but varied number of lipid bilayers in the stacks we will focus on the influence of HA and temperature on the system mechanics.
Please note that you will need to login with your ILL credentials to download the data.
Download DataThe recommended format for citing this dataset in a research publication is in the following format:
STEITZ Roland; DAHINT Reiner; DEME Bruno; Beate Klösgen; KREUZER Martin and SCHNECK Emanuel. (2012). Mechanical properties of bio-membranes interacting with a model synovial fluid. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-646
ILL has partnered with DataCite as the registration agency
for data persistent identifiers.