Interaction between TAT peptide and neutral phospholipid membrane
We are currently investigating the transmembrane mechanism of the cell-penetrating peptide TAT from human immunodeficiency virus. We have used D16 to determine the concentration-dependent distribution of peptide across negatively-charged bilayers and now wish to determine the corresponding distribution for zwitterionic bilayers. The data will complement, and aid in the interpretation of data from other biophysical methods, including differential scanning calorimetry and circular dichroism.
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BRADSHAW Jeremy P; CHEN Xiaochao; CRISTIGLIO Viviana and DEME Bruno. (2015). Interaction between TAT peptide and neutral phospholipid membrane. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-693