Interaction of Rhamnolipids with single model membranes
Biosurfactants have been widely studied in the last years due to their low toxicity, biodegradability and ecological safety. Among biosurfactants, rhamnolipids (RLs) hold a prominent position because of their interesting biological properties such as antimicrobial, antiphytoviral, zoosporicidal activities. Moreover RLs are able to trigger an immune response in Arabidopsis, characterized by signalling molecules accumulation and defense gene activation. The biological activities of natural RLs are highly supposed to be related to their interactions with plasma membranes of target cells. Some studies have been performed to investigate the effects brought by RLs to model lipid membranes, showing their importance in membrane stabilization or destabilization and in regulation of lipid polymorphism, but the detailed molecular mechanism of these interactions is still unknown. In this context, we are studying the structural changes brought by the presence of RLs to complex model membranes by complementary techniques, and we propose to apply neutron reflectometry to investigate the transverse structure modifications brought by RLs presence to different asymmetric model membranes.
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RONDELLI Valeria Maria; BROCCA Paola; CANTU Laura; DEL FAVERO Elena; DELEU Magali; FRAGNETO Giovanna; Mehmet Nail NASIR; POLO LOZANO Damien and TRANQUILLI Nicola. (2016). Interaction of Rhamnolipids with single model membranes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-768
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