Membrane Interlinking by Glycolipids under Defined Repulsive Forces
Glycolipids bearing the neutral LewisX trisaccharide motif have been shown to be able to interlink lipid membranes via favourable saccharide-saccharide interactions, a phenomenon of documented biological relevance. Our recent experiments suggest that this behavior is not a unique property of the LewisX motif, but more prevalent among glycolipids than usually thought. Here we propose the systematic investigation by specular and off-specular neutron diffraction of lipid membranes containing glycolipids with various saccharide headgroups at defined mole fractions. In order to probe the strength of the membrane-interlinking, negatively charged lipids, which exert defined repulsive forces between the membranes, are introduced.
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SCHNECK Emanuel; DEME Bruno; LATZA Victoria and TANAKA Motomu. (2018). Membrane Interlinking by Glycolipids under Defined Repulsive Forces. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-812
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