Antimicrobial action and synergistic interaction of two cationic linear peptides on oriented lipid bilayers - focus on T = 260 - 320 K
We want to complement our previous measurements performed at ILL in June 2018 with data in the range of temperature T = 260 - 320 K. This will slightly extend the range of measurements but more importantly strongly increase the statistics on the data previously recorded. This will permit without any ambiguity the determination of the dynamic and thermodynamic parameters (Enthalpy and Entropy changes) in this region of particular interest where the peptides are biologically active and where we have performed solid-state NMR measurements. Four samples will be made of lipid bilayers (POPE/POPG 3:1), alone or supplemented with peptides (PGLa and/or magainin 2). Elastic incoherent neutron scattering (EINS) measurements will be performed on IN13 - fortunately before it's renewal - to ensure the same experimental conditions.
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BECHINGER Burkhard; CISSE Aline; MARQUETTE Arnaud and PETERS Judith. (2019). Antimicrobial action and synergistic interaction of two cationic linear peptides on oriented lipid bilayers - focus on T = 260 - 320 K. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-856
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