Kinetics of UBX Self-Assembly at the Air/Water Interface
Control of mechanical properties and chemical functionality are key drivers in a range of implanted structures for biomedical applications. This proposal focusses on a new material with the ability to control both of these properties. Ultrabithorax (UBX) protein has been shown to spontaneously self-assemble at the air-water interface to form elastomeric films that can be drawn into fibres or deposited onto a substrate. However, preliminary investigations using laboratory-based techniques have uncovered considerable complexity in the film formation process. In particular, there appears to be a consistent non-monotonic development in the film with time. It appears that the key changes correspond to either submicron lateral structural developments, or structural changes normal to the interface. It is the kinetics of these changes that we would like to probe with neutron reflectivity.
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MACCARINI Marco; ALCARAZ Jean Pierre; GUTFREUND Philipp; HIGGINS Anthony M.; ITALIA Valeria; MARTIN Donald and MEISSNER Kenith. (2020). Kinetics of UBX Self-Assembly at the Air/Water Interface. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-877
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