Relative contribution of the polar moieties of archaeal ether lipids on membrane parameters
We have recently proposed a novel membrane architecture model to explain the stability of lipid bilayers of archaeal cells at high temperatures (> 70°C) and high pressures (400 bar). In this architecture, the increase in membrane stability/rigidity is due to the presence, in the midplane of the bilayer, of apolar hydrocarbons. Our previous experiments (see ILL report 8-02-762 and 8-02-809) have demonstrated that the apolar molecules are located inside the membrane in the midplane of the bilayer. Using different approaches (FTIR, SAXS, DSC), we have demonstrated the impact of the presence of squalane inside the membrane on the physicochemical properties of the bilayer, and especially the predicted increase in stability/rigidity. Membrane parameters depend only partially on core lipid composition, but depend also largely on the polar headgroup properties. In this experiment, we now want to measure the impact of 4 different polar headgroups, more closely related to the natural polar heagroups of Archaea, on membrane properties, in order to evaluate the relative contribution of the polar and apolar moities in membrane physical parameters.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
Phil Oger; Antonino Caliņ; DEME Bruno; LORICCO Josephine; PETERS Judith; SALVADOR CASTELL Marta and TOURTE Maxime. (2020). Relative contribution of the polar moieties of archaeal ether lipids on membrane parameters. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-884
This data is not yet public
This data is not yet public
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