DOI > 10.5291/ILL-DATA.8-02-983

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Title

The role of charge for interaction with bio-membranes: ¿-Synuclein and Synaptobrevin-2

Abstract

In our current research we focus on the interaction of two neuronal IDPs with bio-membranes:¿-Synuclein and Synaptobrevin-2 . We would like to investigate the interaction of both IDP with membranes of varying charge composition (fraction of negative DMPG in neutral DMPC) to examine the configuration in/at the membrane and in the adjacent solution. For ¿-Syn we want to identify the location of ¿-helices and the configuration of disordered regions. For Syb2 we will examine the disordered soluble region with and without the transmembrane region .

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

APANASENKO Irina; BIEHL Ralf; GUTFREUND Philipp; KRUTEVA Margarita; LAKOMEK Nils-Alexander; Nicoḷ Paracini; ROSI Benedetta Petra; SAERBECK Thomas and Andreas M. Stadler. (2023). The role of charge for interaction with bio-membranes: ¿-Synuclein and Synaptobrevin-2. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-983

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Institut Laue-Langevin

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