Impact of tetraethers on the stability of archaeal membranes at high temperature
Archaeal monolayer forming lipids have long been thought to be the major adaptation of the archaeal membrane to extreme conditions. We have proposed and demonstrated a novel membrane architecture model to explain the stability of lipid bilayers in Archaea at high temperatures (> 70°C) and high pressures (400 bar). In this architecture, the increase in membrane stability/rigidity is due to the presence, in the midplane of the bilayer, of apolar hydrocarbons. In our previous experiments (Salvador-Castell 2021), we demonstrated that the presence of the apolar molecule induces phase separation and the appearance of novel phases in the membrane with a P- and T-dependence (ILL report 8-02-852, and LoRicco 2021). We have recently obtained an archaeal strain mutant which is impaired in the synthesis of monolayer forming lipids, and thus can no longer form monolayers. Here, we would like to take this opportunity to explore the relative contribution of the two different types of lipids, diethers and tetraethers, in order to draw a better understanding of bilayer stability in Archaea, and the exact role played by the tetraethers.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
Saracco; DEME Bruno; FONTANAY Stephane; GILLET Priscilla; KORNMUELLER Karin; Phil Oger and PETERS Judith. (2023). Impact of tetraethers on the stability of archaeal membranes at high temperature. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-991
This data is not yet public
This data is not yet public
ILL has partnered with DataCite as the registration agency
for data persistent identifiers.