Characterizing the behavior of a novel archaeal membrane organization with connected membrane leaflets
Extreme archaeal halophiles can grow in conditions where the activity of water is close to zero. Despite an increased intracellular osmolarity, a strong gradient exists between the environment and the cell, and the physico-chemical tolerance of the plasmic membrane to this osmotic stress remains unknown. Part of the increased membrane stability has been associated to the presence of unusual archaeal lipids which have an extended, 25 carbons long, hydrophobic chain in contrast to the 20 carbons long classic chain. These lipids harboring one extended hydrophobic chain could form a zipped bilayer membrane in which the extended chains of lipids from both faces would interact inside the midplane, which would further increase membrane stability. In this experiment, we want to determine the impact of the zip structure on membrane self-organization, structure and resistance to increased temperatures. Using known mixtures of classic and extended lipids, we will be able to quantify the relative contribution of the extended lipids to membrane physical parameters in comparison to the 'classic' archaeal bilayer.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
Phil Oger; DEME Bruno; FONTANAY Stephane; PETERS Judith and Saracco. (2023). Characterizing the behavior of a novel archaeal membrane organization with connected membrane leaflets. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-02-998
This data is not yet public
This data is not yet public
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