The effect of confinement on proteins inside silica tubes investigated using SANS
Confinement of bio-molecules within porous matrices is of significant interest from the biophysical point of view. These porous matrices mimic the conditions of a living cell and hence it helps in studying the various bio-physical processes taking place inside the cell. The interplay of various parameters such as protein-protein, protein-host and confined solvents significantly influence the protein conformations within the hosts. The changes in structure and conformation of protein can only be vividly accounted using neutron scattering techniques. We would like to study using small angle neutron scattering (SANS) (viz. quaternary) structure of hemoglobin entrapped in silica tubes of varying pore diameters.
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BHATTACHARYYA Aninda Jiban; CRISTIGLIO Viviana; GHOSH Rikhia; LINDNER Peter and MANDAL Soumit Sankar. (2013). The effect of confinement on proteins inside silica tubes investigated using SANS. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-03-784