Proton dynamics in malignant glioma tumor
The proposed experiment represents a benchmark in the study of biological tissue with neutrons. From the elementary building blocks of the cell (proteins, membranes etc) to bacteria and in vivo cells, and now to complex brain tissue, neutrons have proven to be unique in pinpointing proton dynamics at atomic scale in biological compounds regardless of the macromolecular complexity involved. The results will be relevant for a deeper understanding of the physical basis of diffusion magnetic resonance imaging technique, nowadays widely used to diagnose brain diseases such as ischemia and tumors.
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NATALI Francesca; DOLCE Caterina; GERELLI YURI; LEDUC Geraldine; OLLIVIER Jacques and PETERS Judith. (2012). Proton dynamics in malignant glioma tumor. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-04-666