RNA Dynamics-Function Relations in Viroids and Ribosomes
RNA displays a rich diversity of properties, which also led to the formulation of the RNA World hypothesis in origin of Life studies, and the nucleic acid field is flourishing with the discovery and characterisation of more and more vital functions involving RNA molecules. In the context of the dynamics-function relation, the proposal is to characterise by neutron scattering the dynamics of RNA molecules with different structures, adapted to different biological function and activity under different environmental conditions: a viroid that may represent a vestige of the RNA world and ribosomal subunits from thermophiles and halophiles.
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RIHOVA Martina; DA SILVA Laura; MAUREL Marie Christine; NATALI Francesca; OLLIVIER Jacques; PETERS Judith; PRIOLO Stefania; RENZI Tatiana; RETICCIOLI Michele; SANCATALDO Giuseppe; SILVANI Raffaele; SILVESTRI Simona; TOZZI Pietro; TRESCA Cesare; XHANI Klejdja; YONATH Ada and ZACCAI Joseph. (2013). RNA Dynamics-Function Relations in Viroids and Ribosomes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-04-687