DOI > 10.5291/ILL-DATA.8-04-696

This proposal is publicly available since 06/07/2018

Title

The effect of lipid environment in dynamics of peripheral myelin protein P2 and effect of P2 to lipid membrane dynamics.

Abstract

The myelin sheath is a multilayered membrane wrapped around axons in the vertebrate nervous system; it enables the rapid transmission of nerve impulses. It contains a set of specific proteins, which are involved in myelin formation and linked to neurological diseases. Here we aim to continue studying the dynamics of myelin peripheral protein P2, its orientation in lipid membrane and effects on membrane dynamics. The proposed experiments are part of a PhD project funded by European Spallation Source (ESS). Short- and long-term ILL visits of the PhD student are planned in the framework of the ongoing collaboration between scientists at ILL (IN13) and the University of Oulu in Finland.

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

LAULUMAA Saara; DEME Bruno; Bernhard Frick; KOZA Michael Marek; KURSULA Petri; NATALI Francesca and OLLIVIER Jacques. (2013). The effect of lipid environment in dynamics of peripheral myelin protein P2 and effect of P2 to lipid membrane dynamics.. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-04-696

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Metadata

Experiment Parameters

  • Environment temperature

    20-310 K

Sample Parameters

  • Formula

    • Peripheral myelin proten P2, wild type
    • Peripheral myelin protein P2, P38G mutated
  • Consistence

    protein enriched lipid membrane
  • Mass

    100 mg