DOI > 10.5291/ILL-DATA.8-04-922

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Title

Global proteome dynamics as a proxy for cellular thermal stability.

Abstract

he biophysical principles at the basis of the adaptation of life to extreme environments are still elusive. Here we propose to study the reversibility of the ns timescale global diffusive contribution to the E. Coli proteome average dynamics after the cell thermal death. We aim at providing a novel biophysical picture of the way fast global protein motions are related to the thermal stability of the very cellular proteome and consequently the temperature range where microbial life can thrive. The results from the spectrometer IN16B will be combined with mesoscale molecular dynamics simulations.

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

DI BARI Daniele; GIUDICI ORTICONI Marie Therese; GUIRAL Marianne; Alessandro Paciaroni; PETERS Judith; SEYDEL Tilo and STERPONE Fabio. (2021). Global proteome dynamics as a proxy for cellular thermal stability.. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-04-922

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