DOI > 10.5291/ILL-DATA.8-04-956

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Title

Adaptation of proteins to high hydrostatic pressure conditions

Abstract

The question of the adaptation mechanism of proteins to a high hydrostatic pressure (HHP) environment is tightly related to possible scenarios for the origin of life. They suggest that it appeared near hydrothermal vents in the depth of the Archaean ocean to prevent the deleterious effects of the young Sun. Thus, the first cells to appear on Earth and their constituents would have been adapted to both High Temperature (HT) and High Hydrostatic Pressure HHP. If the routes to the adaptation to HT are starting to be better understood, adaptive strategies to HHP still remain elusive, and an amino-acidic substitutional pattern has not been found yet. Deciphering these routes is essential to confront the putative deep-sea origins of life and will simultaneously give information on protein folding and adaptation strategies of modern piezophiles.

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

PETERS Judith; Antonino Caliņ; Phil Oger and OLLIVIER Jacques. (2023). Adaptation of proteins to high hydrostatic pressure conditions. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.8-04-956

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