DOI > 10.5291/ILL-DATA.9-10-1739

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Title

Introducing a new ceramide subspecies to ternary Stratum corneum lipid model membranes: CER[NH]

Abstract

All Substances, which want to overcome the skin with the aim to leave or to penetrate into the human body, have to pass the skin' s main barrier, the stratum corneum (SC). Thereby the structural organization of the SC lipids and especially their function in the lipid lamellae play a key role. The heterogeneous group of ceramides (CER), as the main component of the lipid matrix, offers a wide range of influence possibilities. Especially a ternary CER mixture ans its impact to the lamellae forming process and to the barrier function is still an immense point of interest. With the description of a new short-chain CER, a substantial interest in its arrangement within the lipid multilayer system on a molecular level and additionally its influence to the skin' s retarding effect was born. As a part of my habilitation treatise this experiment is very important for the basically understanding of SC lipid arrangements on molecular level.

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

EICHNER Adina; CRISTIGLIO Viviana; DEME Bruno and Thomas Hauß. (2023). Introducing a new ceramide subspecies to ternary Stratum corneum lipid model membranes: CER[NH]. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-10-1739

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