Structure of DNA-bottlebrushes
We have developed a unique well-defined model system for so-called bottle-brush polymers that consists of DNA decorated with physically attached sidechains. The sidechains are genetically engineered hydrophilic polypeptides with short positively charged binding domain that are perfectly monodisperse. For this system we propose to do a precise SANS characterization of both the brush thickness and profile (that, in view of the monodispersity of the system, makes for a good comparison with current polymer brush theories) and of the effective persistence length of the brush-coated DNA. Many conflicting theories exist for the effective persistence lengths of bottlebrushes and our model system in combination with detailed SANS studies offers an ideal opportunity to connect theories and experiments for this highly disputed problem.
Please note that you will need to login with your ILL credentials to download the data.
Download DataThe recommended format for citing this dataset in a research publication is in the following format:
STORM Ingeborg; BORISOV Oleg; LEERMAKERS Frans and SCHWEINS Ralf. (2014). Structure of DNA-bottlebrushes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-11-1697
ILL has partnered with DataCite as the registration agency
for data persistent identifiers.