DOI > 10.5291/ILL-DATA.9-12-428

This proposal is publicly available since 08/30/2021

Title

Coated therapeutic target nanoparticles - D-contrast SANS study of mixed coating stabilization

Abstract

Abstract is not yet public

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

NAWROTH Thomas; DECKER Heinz; FREY Holger; GRILLO Isabelle; HELLMANN Nadja; JOHNSON Raphael; LANGGUTH Peter; SCHMIDBERGER Heinz and SCHWEINS Ralf. (2015). Coated therapeutic target nanoparticles - D-contrast SANS study of mixed coating stabilization. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-12-428

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Metadata

Experiment Parameters

  • Environment temperature

    RT to 37°C

  • Experiment energy

    5; 10 A

  • Experiment moment

    0.001 - 0.3 A-1

  • Experiment res energy

    10 %

Sample Parameters

  • Formula

    • PLGA, Poly-Lactide-Glycolide
    • Cholesteryl-Succinyl-Hexamethylenamido-Glycin
    • HPMC; Hydroxy-Propyl-Methyl-Cellulose
    • Cholesterol
    • Lecithin (DOPC, DMPC, DMPC-d54)
    • CHAPS (detergent)
    • Tween80 (detergent)
    • albumin (bovine, BSA)
    • PLA-hexamethyleneamido-Glycine (PLA = poly-lactide)
    • Cholesteryl-Succinyl-Hexamethylenamido-Glycyl-Thiopropionicacid (lipid-anchor)
    • PLA-Hexamethyleneamido-Glycyl-Thiopropionicacid (polymer-anchor; PLA = poly-lactide)
    • Erbium-Acetate (embeded in PLGA nanoparticles)

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