Nanogel-Protein complex formation at the air/water interface
Nanogel-protein interaction determines the biological fates and functions of these gels when considering their bioavailability and tailored release as drug delivery vehicles. The cell ‘sees’ and interacts with the entire nanoparticle–protein corona complexes rather than with the ‘bare’ entity of nanoparticle because of the large concentration of proteins available in plasma. This proposal is focused for resolving the formation proteins/nanogels complexes and their conformations at air/water interface to develop a robust protocol, aiming to link the chemical structure of nanogels to the interfacial and complex formation behaviour.
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RESMINI Marina; Pengfei Liu; Armando Maestro and ZARBAKHSH Ali. (2020). Nanogel-Protein complex formation at the air/water interface. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-12-588