Internal Dynamics of Biological Hydrogels
Hydrogels are highly interesting with respect to their structure and properties, especially in the context of biology. Here mucus plays a central role and in our experiments we want to study mucus BSM and compare it to a much simplified synthetic hydrogel of PEO/PMAA tailored to possess similar viscoelastic properties. For understanding their transport and viscous properties knowledge of the dynamics of chains and local domains is essential. For obtaining such information NSE with the high contrast in D2O is unique and shall be employed here as a function of hydrogel concentration and also to study the effects of osmolyte and salt, that are known to play important roles in biological hydrogels. In order to cover the relevant size range of 0.5 to 50 nm and the time range of 0.1 to 500 ns IN15 is uniquely suited to give the required information once combined with the SANS experiments done in parallel. Combining the experimental data with theoretical modelling shall then yield a much enhanced insight into the workings of biological hydrogels as they are required in order to advance both fundamental physics research as well as medical application.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
SCHMIDT Robert Franz; BAYDAROGLU Cihan; DAS AVIK; GRADZIELSKI Michael; OMASTA Tomas; PREVOST Sylvain and RULFF Hanna. (2023). Internal Dynamics of Biological Hydrogels. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-1075
This data is not yet public
This data is not yet public
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