Ceramide lipids/Cholesterol/Fatty acid interaction with thermoresponsive nanogels at the air-water interface
Skin is an important target for drug delivery. However the stratum corneum (SC), which is mainly composed of mixture of ceramides, cholesterols and fatty acids, provides a strong barrier to drug penetration. In this proposal we aim to investigate the interaction of thermoresponsive cross-linked organic nanogels with a mixed lipid monolayer of ceramide lipid/cholesterol/fatty acid, designed to mimic the lipid organization of the human SC.
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ZARBAKHSH Ali; Richard A. Campbell; RESMINI Marina; SUN Huihui and ZIELINSKA Katarzyna. (2014). Ceramide lipids/Cholesterol/Fatty acid interaction with thermoresponsive nanogels at the air-water interface. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-530
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