DOI > 10.5291/ILL-DATA.9-13-550

This proposal is publicly available since 10/08/2019

Title

Adsorption of fibrinogen onto stainless steel.

Abstract

With a view to better understanding the interactions between biomedical implants and the body, we propose a study into the surface structure of a key protein, fibrinogen. The aim is to determine the effect of pH, concentration and ionic strength on the adsorption affinity and structural conformation of the protein onto stainless steel. This should aid in understanding the reasons why fibrinogen often denatures on these surfaces and how therefore to prevent internal blood clotting.

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

Mary H. Wood; BARKER Robert; Kathryn Browning and CLARKE Stuart M.. (2014). Adsorption of fibrinogen onto stainless steel.. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-550

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Metadata

Experiment Parameters

Sample Parameters

  • Formula

    • steel substrate
    • fibrinogen