The melting of fiber DNA submerged in D-ethanol/D2O mixtures.
We would like to study the spatial correlations of the DNA molecules submerged in D-ethanol/water mixtures during the melting transition or thermal denaturation of DNA. Neutron scattering can access spatial information which is fundamental for a total understanding of the transition. We have performed this kind of experiments with relative success in humidified fibers and fibers immersed in polyethylene glycol (PEG) solutions. Now we wish to study the melting in ethanol since preliminary measurements have shown a significant difference in the dynamics of the transition with respect to fibers in PEG solution. Namely, the transition seems to be steadier in ethanol/water mixtures which could hint to a different interaction between DNA and solution in these environments. In addition, it is feasible to use deuterated ethanol for composing the solutions so the proton background is lower than in the PEG case and our analysis may be accurate.
Please note that you will need to login with your ILL credentials to download the data.
Download DataThe recommended format for citing this dataset in a research publication is in the following format:
Adrian Gonzalez; S. Cuesta-Lopez; DEME Bruno; FORSYTH Victor Trevor; JOHNSON Mark Robert; MARTY RODA Marta; MOSSOU Estelle; PEYRARD Michel; THEODORAKOPOULOS Nikos and WILDES Andrew. (2016). The melting of fiber DNA submerged in D-ethanol/D2O mixtures.. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-678
ILL has partnered with DataCite as the registration agency
for data persistent identifiers.