Interaction of cellulose nanocrystals with lipid membranes
A better understanding of the structure of plant cell walls is a major challenge from both soft matter and biological points of view. In the plant kingdom, one of the first stages of plant cell wall construction is the deposition of cellulose microfibrils on the external leaflet of a lipidic membrane. In this context, CERMAV has recently developed biomimetic constructs in which cellulose nanocrystals (CNCs) were deposited on the surface of a lipid membrane, serving both as a basic model of plant cell wall and as innovative biomaterials. Preliminary QCM-D experiments allowed us to identify some key parameters governing this interaction. However, the structural features of such 2D constructs are yet to be investigated. In the proposed experiment, neutron reflectivity will be used to study the influence of pH, CNC concentration and the type of lipids (including the use of biologically relevant glycolipids) on the dimensions, composition and morphology of the formed assemblies, which will lay the foundation for the creation of novel biomimetic constructs made from CNCs and lipids.
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HEUX Laurent; Emily D. Cranston; FRAGNETO Giovanna; JEAN Bruno and NAVON Yotam. (2018). Interaction of cellulose nanocrystals with lipid membranes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-731
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