Floating Lipid Bilayer supported by PEG Brushes
For decades, floating lipid bilayers supported by soft polymer brushes or cushions have been considered ideal platforms for structural and functional studies of lipid bilayers and biological membranes. But despite great efforts,most of the conceived sample architectures did not meet the expectations, because the polymer brushes typically collapse due to strong favourable interactions between the lipids and commonly used solid supports. Here, we propose the structural investigation by neutron reflectometry of brush-supported floating bilayers in the form of a triple-monolayer architecture realized by using a Langmuir/Schaefer - Langmuir/Blodgett - Langmuir/Schafer transfer procedure. With this architecture we have already obtained promising preliminary results.
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SCHNECK Emanuel; FRAGNETO Giovanna; GUTFREUND Philipp; LATZA Victoria; MICCIULLA Samantha and Ernesto Scoppola. (2018). Floating Lipid Bilayer supported by PEG Brushes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-776
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