Gelation and aggregation behavior of green composit hydrogels derived from regenerated silk fibroin
Silk fibroin (SF) is a biocompatible and –degradable material that has raised interest for applications in the biomedical field. SF is regenerated from the cocoon of the silkworm in a degumming and dissolution process, which often degrades the protein and alters its properties. Here we want to study novel hybrid silk fibroin based gels that use regenerated SF in its native form. We combine these gels with Sophorolipids (SL) to form a green composite hydrogel. SL are microbially produced glycolipids with anti-microbial, anti-inflammatory and anti-cancer properties. Micellar SL were reported to form hydrogels with fragmented SF with adjustable pore sizes and application as 3D scaffolds. We want to combine SL in their micellar and non-micellar form with native SF to join their inherent biomedical properties.
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LASSENBERGER Andrea; BACCILE Niki; MARTEL Anne and SEYRIG Chloe. (2018). Gelation and aggregation behavior of green composit hydrogels derived from regenerated silk fibroin. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-778
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