IN-SITU STUDY OF THE EFFECT OF GRAPHENE OXIDE NANOPARTICLES ON THE SURFACE PROPERTIES OF DIPALMITOYLPHOSPHATIDYLCHOLINE
The increasing exposure to graphene oxide nanoparticles, GO, used in a great number of technological applications, makes necessary a deeper comprehension of the potential risk and hazards related to this material for both the environment and health. Since the lungs are an important entry point of GO, one of the most important aspects is the effect that these particles produce on the respiratory function. 1,2 dipalmitoylphosphatidylcholine, DPPC is the major component of the lung surfactant and is responsible for the decrease of the surface tension and the mechanical stability of the lungs during respiratory cycles. Therefore, the study of the interaction between DPPC and GO becomes necessary to understand the potential adverse effects on respiratory functionality. Because the lung surfactant is confined between air and the alveolar cavity, Langmuir monolayers of DPPC are a good model to mimic the effect of GO nanoparticles on the interface air-liquid at the lungs. Accordingly, the main objective of this Neutron Reflectometry experiment is to develop microscopic understanding of the effect of GO on the thickness and coverage of DPPC films on the air-water interfaces.
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M. M Velázquez; Armando Maestro and M. D. Merchán. (2019). IN-SITU STUDY OF THE EFFECT OF GRAPHENE OXIDE NANOPARTICLES ON THE SURFACE PROPERTIES OF DIPALMITOYLPHOSPHATIDYLCHOLINE. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-843
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