Measuring the bending modulus of lamellar gels composed of new microbial glycolipids
Microbial glycolipids are natural molecules obtained from the microbial digestion of fatty acids and sugars. They have low toxicity, high biodegradability and their synthesis process (industrial microbiology) is environmentally friendly. The most important molecules studied so far are called sophorolipids, rhamnolipids and glucolipids. All of them have in common a sugar headgroup (sophorose, rhamnose or glucose) covalently bonded to a lipid with a free COOH group available at the other end of the molecule. They have been initially developed as green detergents to replace petrochemical ones, but this seemingly promising usage starts to be disregarded due to the high cost/benefit ratio. In a recent set of works we have shown that a single-glucose lipid forms lamellar hydrogels, which can then open new perspectives of applications. We found that the hydrogel elastic properties depend on pH and ionic strength. We believe that the bending modulus of the lipid membrane is important for the gel properties and that the modulus vary with pH and ionic strength. However, the modulus is unknown for this new class of lipids and we aim at measuring it using neutron spin echo experiments.
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BACCILE Niki; HOFFMANN Ingo and POIRIER Alexandre. (2020). Measuring the bending modulus of lamellar gels composed of new microbial glycolipids. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-915