DOI > 10.5291/ILL-DATA.CRG-2739

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Title

Nanoparticle-supported lipid bilayers (NP-SLB), a new platform to study curvature-induced lipid segregation by neutron reflectometry

Abstract

The importance of lipids and protein lateral organization within biological membranes has recently emerged as a prominent research area in bio-membranes. However, the challenges posed by the complexity of these systems require simple in vitro models to study the compartmentalization and clustering of macromolecules on the membrane plane with sub nanometer resolution. One of the ways protein and lipids form domains in membranes is by co-localizing in regions of high curvature, such as at the polar regions of rod shaped cells. Here, we introduce a novel model membrane to study the effect of curvature on lipid and protein segregation, which will provide complementary information to the fluorescence microscopy techniques used in this area of research

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

Nicoḷ Paracini; CARDENAS; Christopher J. Garvey; VOROBIEV Alexei and WOLFF Maximilian. (2020). Nanoparticle-supported lipid bilayers (NP-SLB), a new platform to study curvature-induced lipid segregation by neutron reflectometry. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.CRG-2739

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