Density of states and EINS of protonated and deuterated GFP in view of an analysis including quantum effects
There is a growing number of indications that quantum mechanics might play a role for the functioning of certain biomolecules, as for instance through tunnelling effects or quantum entanglement. As quantum effects depend on the mass of the scatterer, their signature should be detectable when comparing a protonated protein with its per-deuterated counterpart. We use both versions of GFP powders (already disposable). We propose to record the density of states at low temperature over a broad energy domain to permit data analysis within a newly developed approach taking into account quantum effects. Former analysis on IN5 displayed bad resolution results over 150 meV, which unabled us to investigate all internal motions and normalise our data. We will measure the general densities of states on IN1 Lagrange up to 300 meV, at a temperature of 2.5 K using a displex for cooling. Thus we will have complementary results to our Panther experiment, in term of energy and Q range (this proposal is already accepted for next beamtime). We ask for 4 hours of measurement per sample (2 of them), and 4 hours for the corrections (empty cell and vanadium), in total 1 day of beamtime for Lagrange.
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NIDRICHE Agathe and JIMENEZ RUIZ Monica. (2021). Density of states and EINS of protonated and deuterated GFP in view of an analysis including quantum effects. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.EASY-881
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