Microstructure of poly-L-lysine (PLL) single chain nanoparticles: the role of the precursor conformation
Single chain nanoparticles (SCNPs) are unimolecular polymer chains folded or collapsed via intra-molecular cross-linking under high dilution, leading to sparse conformations and a topological polydispersity similar to that of intrinsically disordered proteins. Due to their small size, softness, and internal compartmentalization they have applications in catalysis, sensing and drug delivery. To extend SCNPs to polypeptides, it is important to understand the role of the chain conformation of the precursor on the resulting SCNP morphology. This proposal aims to probe the conformation of SCNPs based on the polyelectrolyte poly-L-lysine (PLL) using SANS. We hypothesize that the polymer conformation has an important role on the balance between inter and intramolecular cross-linking as well as on the internal morphology of the SCNPs.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
Paula Malo de Molina; Arantxa Arbe; COLMENERO Juan; LE Thu Phuong; POMPOSO Jose A. and PORCAR Lionel. (2023). Microstructure of poly-L-lysine (PLL) single chain nanoparticles: the role of the precursor conformation. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-10-1761
This data is not yet public
This data is not yet public
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