DOI > 10.5291/ILL-DATA.9-13-1086

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Title

Coexisting planar and curved model membranes

Abstract

The vast majority of studies published in the literature regarding the curvature of biological membranes and curvature-related phenomena are based on fluorescence microscopy techniques which, in the best cases, are limited to a spatial resolution of hundreds of nanometres and require the use of lipids chemically modified with fluorophores to enable their detection. To increase the resolution down to sub nanometre distances, real-space techniques such as microscopy must be complemented with reciprocal-space methods such as neutron scattering. However, there are currently very few model membranes amenable to be used in the study of curvature-related lipid sortingusing scattering techniques. Our goal is to tackle this open challenge by creating a supported lipid bilayer on top of an ordered array of hexagonally packed silica nanospheres and use them to study lipid demixing as a function of curvature. We have shown that we can make such samples by microscopy and neutron reflection and now we plan to study lipid demixing at different curvature using pi-gisans

Experimental Report

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Data Citation

The recommended format for citing this dataset in a research publication is in the following format:

CARDENAS; GVARAMIA Manuchar; KYZYMA Olena; MEHLER Filip; NAKAMURA Hirona; Bert Nickel; VOROBIEV Alexei and WOLFF Maximilian. (2023). Coexisting planar and curved model membranes. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.9-13-1086

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