Surfactant Modified Salivary Pellicles
Surfactants are often used in oral health products. The use these compounds has been related to several oral diseases. However, oral care products without surfactants have been unsuccessful as these components fulfil several functions. They serve as solubilizing, dispersing, emulsifying and wetting agents. They also promote foaming which provides a perception of cleanliness. Thus, a widespread use of oral care formulations without surfactants is unrealistic. It is then of interest to identify those with lower adverse effects. In this context, it is of great value to understand how surfactants interact with the first interfacial layer that they encounter i.e., salivary pellicles. These are proteinaceous nm-thick films that form on any type of surface upon exposure to saliva and that fulfil many functions e.g., they protect, lubricate and hydrate underlying oral tissues. The applicants have previously shown that Neutron Reflectometry (NR) is a powerful tool to investigate the structure of salivary pellicles. Here, we propose to use NR to study how their structure is affected by surfactants of relevance within oral care formulations.
The data is currently only available to download if you are a member of the proposal team.
The recommended format for citing this dataset in a research publication is in the following format:
Juan Francisco; ARNEBRANT Thomas; BARKER Robert; H Boyd; Christopher J. Garvey; GUTFREUND Philipp; KLECHIKOV Alexey; MEYER Gautier; PLAZANET Marie; SOTRES Javier; VOROBIEV Alexei and WELBOURN Rebecca. (2018). Surfactant Modified Salivary Pellicles. Institut Laue-Langevin (ILL) doi:10.5291/ILL-DATA.CRG-2539
This data is not yet public
This data is not yet public
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